FDA ESG

Step 1: Request a WebTrader Test Account

Step 2: Order Client Digital Certificate

Step 3: Download and Install the Certificate

Step 4: Export Public Key

Step 5: Set Up a Test Account

Step 6: Complete a Test Submission

Common Errors

FDA Checklist & FAQs (PersonalSign)

The Food and Drug Administration (FDA) Electronic Submissions Gateway (ESG) is an Agency-wide solution for accepting electronic regulatory submissions. The FDA ESG enables the secure submission of regulatory information for review.

Secure E-Mail - FDA

The FDA uses self-signed certificates so the process for this is slightly different than standard S/MIME with trusted certificates.

Update Public Key - FDA ESG (Renewals & Reissues)

This article provides step-by-step instructions for updating the public key in your FDA ESG account. This is necessary if you reissued or renewed your Client Digital Certificate. If this is not the solution you are looking for, please search for your solution in the search bar above.